All configurationsSome configurationsNoneNot reported by EPA
Configurations by year
2026 Lexus IS
2 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2025 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 500
5.0L 8-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
2024 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 500
5.0L 8-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
2023 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 500
5.0L 8-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
2022 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 500
5.0L 8-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
2021 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2020 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2019 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2018 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 300
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2017 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 200t
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2016 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 200t
2.0L 4-cyl turbo
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 300 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
2015 Lexus IS
6 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 250 C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350 C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
2014 Lexus IS
6 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 250 C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
IS 350
3.5L 6-cyl
8-speed automaticS8
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350 C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
2013 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
No
Premium
No
IS 350/IS 350C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
No
Premium
No
2012 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed manual6-spd
Rear-Wheel
Not reported
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
Not reported
Premium
No
IS 350/IS 350C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
2011 Lexus IS
5 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed manual6-spd
Rear-Wheel
Not reported
Premium
No
IS 350 AWD
3.5L 6-cyl
6-speed automaticS6
All-Wheel
Not reported
Premium
No
IS 350/IS 350C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
2010 Lexus IS
4 configurations
EPA model name
Engine
Transmission
Drive
Start-stop
EPA test fuel
Flex-fuel
IS 250 AWD
2.5L 6-cyl
6-speed automaticS6
All-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
IS 250/IS 250C
2.5L 6-cyl
6-speed manual6-spd
Rear-Wheel
Not reported
Premium
No
IS 350/IS 350C
3.5L 6-cyl
6-speed automaticS6
Rear-Wheel
Not reported
Premium
No
Check before you buy or refuel Confirm on the window sticker, owner's manual or with the dealer. Trims and options can differ from the configurations EPA tested.
About premium fuel EPA data shows the fuel a vehicle was tested on. It does not say whether premium is required or only recommended. Your owner's manual or fuel-door label is the authority.
Before using E85 Confirm the vehicle is a flex-fuel vehicle (FFV) in the owner's manual, or look for a yellow gas cap or an "FFV" badge. Not every version of a model is flex-fuel.